| EPIC-2.2002.pdf | Most Recent Version of EPIC |
| EPIC-26-6.2002.pdf | 26-item short-form version of EPIC |
| EPIC-AUASI-SF12-2.2002.pdf | EPIC + SF12 and AUASI |
| EPIC-Urinary-2.2002.pdf | EPIC - Urinary Domain only |
| EPIC-Bowel-2.2002.pdf | EPIC - Bowel Domain only |
| EPIC-Sexual-2.2002.pdf | EPIC - Sexual Domain only |
| EPIC-Hormonal-2.2002.pdf | EPIC - Hormonal Domain only |
| EPIC-Demog-2.2002.pdf | EPIC - Demographics add-on* |
Click here for a list of updates.
| Validation.pdf | "Development and Validation of the Expanded Prostate Cancer Index Composite (EPIC) for Comprehensive Assessment of Health-Related Quality of Life in Men with Prostate Cancer", Urology. 56: 899-905, 2000. |
| Cross-sectional.pdf | "Comprehensive comparison of health-related quality of life after contemporary therapies for localized prostate cancer ", Journal of Clinical Oncology. 20(2): 557-66, 2002. |
| Brachytherapy.pdf | "Neoadjuvant hormonal therapy and older age are associated with adverse sexual health-related quality-of-life outcome after prostate brachytherapy ", Urology. 59: 480-4, 2002. |
| Radical Prostatectomy.pdf | "Determinants of Long-Term Sexual HRQOL After Radical Prostatectomy Measured by a Validated Instrument", Journal of Urology. 169: 1453-7, 2003. |
| EPIC-Scoring-2.2002.pdf | Scoring Documentation |
| Scoring-2.2002.sas | SAS Macro for scoring EPIC* |
| Scoring-epic26-6.2002.sas | SAS Macro for scoring EPIC-26* |
* Choose the 'Save to Disk' option after clicking on the SAS Macro name. If your browser displays the macro on the screen as a text file. Choose File -> Save As, and then choose a location to save the macro.
| Number of EPIC domains as primary endpoints | Domain-specific significance level (for overall significance of 5%) | Potential Endpoints | Required Sample Size Per Treatment Group (Based on Effect Size of 0.5) | |
|---|---|---|---|---|
| 80% Power | 90% Power | |||
| 1 | 0.05 | Any 1 of the summary scores - Urinary, Bowel, Sexual, Hormonal | 64 | 86 |
| 4 | 0.0125 | Urinary, Bowel, Sexual, and Hormonal Summary Scores | 91 | 116 |
| 5 | 0.01 | Urinary Irritative, Urinary Incontinence, Bowel, Sexual, and Hormonal Summary Scores | 96 | 121 |
| 6 | 0.0083 | Urinary Irritative, Urinary Incontinence, Bowel, Sexual, and Hormonal Summary Scores and SF-12 PCS | 99 | 125 |
| 10 | 0.005 | Urinary Irritative, Urinary Incontinence, and Function and Bother subscales for Urinary, Bowel, Sexual, and Hormonal Domains | 109 | 136 |
| 12 | 0.0042 | Urinary Irritative, Urinary Incontinence, Function and Bother subscales for Urinary, Bowel, Sexual, and Hormonal Domains, and SF-12 PCS and MCS Scores | 112 | 140 |
| Document | Description |
|---|---|
| Norms.pdf | Characteristics of EPIC domain-specific summary and subscale scores for 112 controls without prostate cancer |
| Document | Description |
|---|---|
| epic26web.pdf | Statistics for the validation process of the EPIC-26 |
What is EPIC?
EPIC is a comprehensive instrument designed to evaluate patient function and bother after prostate cancer treatment.
Am I allowed to make copies of EPIC?
Yes, you are free to make copies and distribute EPIC.
Do I need to pay a fee to use EPIC?
No, there is no fee required to use EPIC.
When reporting my findings, what article should I reference?
For any manuscript published that uses EPIC, you should reference the EPIC validation paper published in the December 2000 issue of Urology. The full reference is:
Wei J, Dunn R, Litwin M, Sandler H, and Sanda M. "Development and Validation of the Expanded Prostate Cancer Index Composite (EPIC) for Comprehensive Assessment of Health-Related Quality of Life in Men with Prostate Cancer", Urology. 56: 899-905, 2000.
How come I cannot open the PDF files?
This is most likely due to the fact that you are either not using Adobe
Acrobat Reader or are using a previous version of the reader. These files
were created using version 4.0 of Adobe Acrobat, so version 4.0x or higher
of the
reader is required to view them. This is available as a FREE download, which can be obtained by clicking on the following icon:
| Martin G. Sanda, M.D. | John T. Wei, M.D. | Mark S. Litwin, M.D., M.P.H. |
| Division of Urology | University of Michigan | UCLA Department of Urology |
| Beth Israel-Deaconess Medical Center | 2916 Taubman Center | Box 951738 |
| 330 Brookline Ave | 1500 E. Medical Center Dr. | Los Angeles, CA 90095-1738 |
| Boston, MA 02215 | Ann Arbor, MI 48109-0330 | Phone: (310) 794-7960 |
| Phone: (617) 667-2960 | Phone: (734) 615-3040 | Fax: (310) 206-5343 |
| Fax: (617) 667-3013 | Fax: (734) 936-9127 | Email: mlitwin@mednet.ucla.edu |
| Email: msanda@bidmc.harvard.edu | Email: jtwei@med.umich.edu |
For information on the use of the SAS scoring macro, please contact:
| Rodney L. Dunn, M.S. |
| 300 N. Ingalls, 8D15 |
| Ann Arbor, MI 48109-0473 |
| Phone: (734) 615-1396 |
| Fax: (734) 936-9582 |
| Email: rldunn@umich.edu |